Firefighters Union Warns Against Unproven Smoke Supplement
Firefighters Union Warns Against Unproven Smoke Supplement
The News
Fire and medical officials are warning Western wildland firefighters against glutathione, a supplement offered to crews exposed to toxic smoke that has not been proven safe or effective, according to reporting by the Associated Press.
The supplement is delivered by IV or through a nebulizer, an inhaler-like machine. At least two pharmacies recalled it in August after finding bacterial contamination during lab testing — one said it had received reports of people suffering fever, chills and severe headaches.
"Because glutathione is not an FDA-approved drug, consumers should be cautious about product safety and claims that glutathione can treat or prevent diseases," said a safety advisory issued last week by the International Association of Firefighters, a labor union representing some 360,000 first responders.
Timeline
A blaze destroys thousands of homes in California's wine country. A group of naturopaths called The Integrative Health Action Network begins its work with firefighters.
The group provides glutathione to firefighters during the wildfires that tear through Los Angeles County.
The California Board of Pharmacy reverses course on regulations that would have made the supplement harder to acquire, after pushback from some firefighters.
Glutathione is offered to crews fighting blazes that destroyed hundreds of buildings in and around Spokane, Washington. At morning briefings, medical unit leaders on scene from California urged crews to check out a tent where the nonprofit, run by licensed naturopathic doctors, offered the supplement.
At least two pharmacies recall the supplement over bacterial contamination.
The IAFF issues its safety advisory.
Reactions
Sean DeCrane, the IAFF's assistant to the general president for health and safety, said the supplement's promotion in Spokane prompted physicians and some union members to contact the IAFF with concerns about health claims that no research backs. The union also received reports that some firefighters felt worse or became sick after being treated, he said, and argued that treatments marketed to firefighters should be tested for unintended consequences.
Jen Riegle, a naturopathic doctor and co-founder of The Integrative Health Action Network, responded to the advisory by saying the organization recognizes the need for peer-reviewed research on whether glutathione can reduce chemical burdens in firefighters and is "actively exploring partnerships to that end."
Some firefighters say it works. Pasadena Fire Captain Matt Caffey, a paramedic for 28 years who fought last year's Eaton fire in Southern California, described what smoke from burning neighborhoods does: coughing, vomiting and brain fog. "You can't remember things. You're just so behind the eight ball. You can't catch up. You're not recovering," he said. Caffey urged Integrative Health Action Network providers to come to Spokane.
Doctors say the anecdotes are not proof. Dr. Cora Sack, a pulmonary specialist in environmental and occupational lung disease at the University of Washington School of Medicine, called the claims "interesting and provocative and deserve further study," but added that "we lack clinical evidence of its efficacy." Luke Montrose, a Colorado State University professor whose research covers wildfire smoke and disease risk, said glutathione has anti-inflammatory properties, "but because it hasn't been studied, I'm hesitant."
What's Next
The IAFF advisory is a warning, not a ban — glutathione remains available, and the California Board of Pharmacy has already backed off tighter restrictions once under pressure from firefighters. The Integrative Health Action Network says it is looking for research partners to study whether the supplement does anything.
Sack said the case for study rests on biology, not results: wildfire smoke creates oxidative stress in the body, and there is an "interesting biological plausibility" to think antioxidants could affect that. She does not endorse its use without clear evidence.
More
Glutathione is an antioxidant made primarily in the liver that neutralizes unstable molecules that attack the body and cause cellular damage. Taken through a nebulizer, it may constrict the airways of people with asthma or chronic lung conditions, Sack said. It is processed in sterile compounding pharmacies, and there have been cases of people being poisoned by contamination at such facilities. Injecting a contaminated product "could cause significant medical events including fevers, hypotension, inflammatory reactions, anaphylactic shock and death," according to the recent recalls.
The underlying problem is real. Wildfire smoke is especially toxic when fires burn through urban areas and consume household appliances, batteries and chemicals, and tens of thousands of people die annually in the U.S. from the long-term effects, the AP reported. Firefighters work in conditions that make a respirator with an oxygen tank impractical, DeCrane said, leaving them exposed to a "slew of chemicals" with short- and long-term health consequences.
Reporting from the Associated Press, The Independent and The Boston Globe.
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