US Firm's Weight-Loss Pill Launches First in Britain
US Firm's Weight-Loss Pill Launches First in Britain
The News
A once-daily weight-loss and diabetes pill made by the American drugmaker Eli Lilly went on sale in UK pharmacies on Monday, making Britain the first country in Europe to approve it.
The drug is orforglipron, sold under the brand name Foundayo. Lilly, the US firm behind the injectable Mounjaro, had the pill authorised by Britain's Medicines and Healthcare products Regulatory Agency earlier this month.
It is the second GLP-1 weight-loss pill to reach UK pharmacy shelves, and it arrives on private prescription only — not yet on the National Health Service.
What The Pill Does
Foundayo is licensed for people with a body mass index of 30 or higher, or a BMI between 27 and 30 with at least one weight-related condition. It can also be used to improve blood sugar in patients with poorly controlled type 2 diabetes.
It is taken once a day, at any time, with no food or water restrictions.
Dosing starts at 0.8mg and climbs through 2.5mg, 5.5mg, 9mg, 14.5mg and 17.2mg, with patients spending a minimum of one month at each level.
Timeline
The MHRA approves the first GLP-1 pill for weight loss, a tablet form of Wegovy.
That Wegovy tablet becomes available through UK pharmacies.
The MHRA authorises orforglipron, branded Foundayo, making the UK the first country in Europe to clear it.
Foundayo goes on sale in UK pharmacies on private prescription.
Reactions
"The UK is the first country in Europe where Foundayo is now available," said Khalil Asmar, vice-president of cardiometabolic health at Lilly Northern Europe. "We're pleased that this means there is another oral treatment option for eligible UK patients alongside licensed injectable treatments."
Henry Gregg, chief executive of the National Pharmacy Association, called it "another significant day with a second weight loss pill available from today in certain pharmacies," adding that it "is particularly significant for patients who cannot or do not want to take an injectable medicine and could make weight-loss treatment available to a wider range of patients."
Gregg also issued a warning about fakes: "It is easier for criminals to provide fake, unlicensed or counterfeit versions of oral medications than injectables and patients must make sure they only access weight loss treatments through safe and regulated pharmacies."
He pressed the government and the NHS to use pharmacies to get the drugs to eligible patients, rather than what he called "the current postcode lottery that exists for weight management services via GPs."
What's Next
Eli Lilly says it is working with the National Institute for Health and Care Excellence, the NHS spending watchdog, on its assessment of Foundayo for a potential rollout on the health service in England. Until then, British patients pay privately.
More
The counterfeit warning is not hypothetical. The Guardian reports the MHRA seized £250,000-worth of unlicensed weight-loss pens and ingredients from a factory in Northampton last year, and that Eli Lilly is suing various suppliers it accuses of taking part in an illegal hidden market for its drugs. Pills are easier to counterfeit than injectables, which is why pharmacists are telling patients to buy only through regulated pharmacies.
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